Wednesday, 19th November

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Speakers

9:00AM - 10:05AM

Heritage Ballroom

Organelle quality control in neuronal homeostasis and neurodegeneration - Erika Holzbaur
On the degradability of Tau aggregates by autophagy - Bernd Bauer
Autophagic regulation of RNAs in neurons - Vassiliki Nikoletopoulou

10:05AM - 10:30AM

Wednesday, 19th November

Convention Centre

10:30AM - 11:25AM

Wednesday, 19th November

Heritage Ballroom

Autophagy and its roles in neurodegeneration - David C Rubinsztein
Autophagy regulator ATG7 links lipid metabolism to cell-fate decisions in kidney tubule health and disease - Alessandro Luciani
BECLIN1 as a gatekeeper of intestinal resilience - Erinna F Lee

11:25AM - 12:00PM

Wednesday, 19th November

Heritage Ballroom

Reversible One-way Lipid Transfer at ER-Autophagosome Membrane Contact Sites via Atg2 - Li Hao
A structural and regulatory framework for Atg9-containing vesicle formation and their Atg1-dependent remodelling during autophagy initiation - Ella Knüpling
STING-OPTN axis bridges mitophagy and cell fate decisions - Guang LU
Lipid ubiquitination: detecting and characterising a new cellular signalling pathway - Laura Fielden
The Drosophila Zer1 interacts with Ref(2)P to regulate autophagy and Keap1-Nrf2-mediated oxidative stress - YI TING WANG
Lysosomal protein abundance and localisation alterations in neurons with TDP-43 pathology in neurodegenerative disease - Natalie Clubley

12:00PM - 12:20PM

Wednesday, 19th November

Mantra Lawn Area

12:20PM - 1:20PM

Wednesday, 19th November

Convention Centre

1:20PM - 3:20PM

Wednesday, 19th November

Convention Centre

Effect of Metformin on Mitophagy and Lipophagy in Breast Cancer Cells - Ayan Nurkesh
Determine the role of ULK1-mediated p62 phosphorylation in FUS-ALS - Jing LU
TECPR2 regulates collagen processing by maintaining transferrin dependent iron homeostasis and links to respiratory dysfunction in HSAN9 - Olee Gogoi
Novel strategies for ATG16 in Atg8ylation - Alf Håkon Lystad
Mitophagy enhancer Rhapontigenin exerts neuroprotection in drosophila and mice models of Parkinson's disease - Liming XIE
Decipher the intricate relationships between UPS and PINK1-Parkin mitophagy - Yichi Zhang
Utilizing recent advances in machine learning for LIR predictions - Jan F. M. Stuke
Autophagy captures the retromer-TBC1D5 complex to inhibit receptor recycling - Julian M Carosi
A novel lipophagy reporter for potential diagnosis of lysosomal storage diseases - Yuning Hong
Epigenetic regulation of PARK2 and its implication in cancer - Shuai You
CAMSAP3 Regulates Lysosomal Positioning and Activity via Golgi-Derived Microtubules under Nutrient Deprivation - Kuei-Hsiang Pan
The Neuroprotective Effect of p62 Against PolyG Toxicity in Neuronal Intranuclear Inclusion Disease: Nuclear Protein Sequestration and Autophagic Adaptation - Yu-Jung (Rennie) Tsao
NS1-BP as a Modulator of Stress Granule Dynamics and Autophagy in Neurodegeneration - Hyun-Ji H Ham
Role of LIR-mediated mATG8s function in neuronal autophagy and social recognition memory - Semin Park
STONIN2, a novel therapeutic target of Bacopasaponin C promotes lysosome-mediated cell death in oral cancer - Amruta Singh
The small GTPase Rab7 plays an essential role in Ulk1/Rab9-dependent alternative autophagy - Jihoon Nah
Targeting autosis in Triple Negative Breast Cancer via autophagy-inducing stapled peptide - Xiaozhe Zhang
A Golgi-to-Lysosome Trafficking Pathway for Selective Protein Degradation - Hsiang-Yi Chang
PPA2 activates pre-DNM1L constriction signalling to control mitochondrial biogenesis and degradation - Sujit Kumar Bhutia
Cationic Nanoplastics Impair Lysosomal Function and Autophagic Flux to Promote Pro-inflammatory Activation of Microglia - Jie Xiao
Rubicon promotes hepatocellular carcinoma via suppressing selective removal of cell cycle regulators - Hitomi Imoto
Phase separation promotes Atg8 lipidation and vesicle condensation for autophagy progression - Yuko Fujioka
BECLIN1: a novel master regulator of intestinal homeostasis - Doug Fairlie
Initiation mechanisms in PINK1/Parkin mitophagy - Thanh Nguyen
A Role of selective autophagy in hepatitis C virus infection - Chieko Matsui
A novel pH-sensitive probe to quantify autophagy on high throughput/content imaging platforms - Peter J Wookey
Proteomic Landscape of LC3 and GABARAP Reveals Lipidation-Dependent Differential Roles in Neurons - Haneul Choi
Identification of the YIPF3-YIPF4 complex as a Golgiphagy receptor - Akiko Kuma
SnRK1-mediated phosphorylation of SH3P2 balances autophagy and endocytosis in Arabidopsis plants - Kai Ching Law
Lipid ubiquitination: detecting and characterising a new cellular signalling pathway - Laura Fielden
Atg15 is a vacuolar phospholipase that disintegrates organelle membranes - Kuninori Suzuki
Glycogen ubiquitination and its role in catabolism - Simon Cobbold
p53 protects adult hippocampal neural stem cells from psychological stress by preventing autophagic cell death - Hyeonjeong Jeong
Novel Motif in Several Proteins Interacting with a Lysosomal Membrane Integral Protein Implies a Link between Ubiquitylation, Autophagy, and Ciliogenesis - Prosenjit Pal
Unveiling the Mechanism of Plant Autophagosome Turnover: Vacuolar SNARE SYP22 Mediates Autophagosome-Vacuole Fusion in Arabidopsis - Hyera Jung
Spatiotemporal dynamics of physiological mitophagy in aging brain circuits - Anna Rappe
WBP2 connects Vesicle-Coat Proteins and Autophagosome Maturation - Stephanie Kaeser-Pebernard
Identifying novel regulators of p62 body-selective autophagy via purification of phase-separated condensates - Hideaki Morishita
Plasma membrane-to-lysosome FGR signaling regulates endocytosis-associated lysosome homeostasis - Chonglin Yang
A structural and regulatory framework for Atg9-containing vesicle formation and their Atg1-dependent remodelling during autophagy initiation - Ella Knüpling
Cholesterol dynamics coincides with ER clearance during development - Ziyang Li
TXNIP Redirects p21-Dependent Autophagy Toward Apoptosis in HepG2 Cells Under Lipotoxic Stress - Minkyung M.K. Cho
ZPR9 interacts with ULK1 to regulate autophagy in liver cell. - JUNGKEUN OH
SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity - Yanzhe Zheng

3:20PM - 4:15PM

Wednesday, 19th November

Heritage Ballroom

Autophagy-Driven Targeting of PC Synthesis Enzymes to Forming Autophagosomes - Zvulun Elazar
Plant-specific mitochondrial fission machinery connects mitochondrial dynamics and mitophagosome formation for piecemeal mitophagy - Xiaohong Zhuang
Mitochondria are destroyed by microautophagy in macrophages - Shiou-Ling Lu

4:15PM - 4:40PM

Wednesday, 19th November

Convention Centre

4:40PM - 6:00PM

Wednesday, 19th November

Heritage Ballroom

PISD-a switch between lipophagy and lipid droplet-to-mitochondria fatty acid transfer - Yan G. Zhao
‘Resolving’ the role of tubular lysosomes in bone-digesting giants - Nathan Pavlos
Suppression of autophagic lysosome reformation as a new pathomechanism linking genetically distinct muscular dystrophies and myopathies - Randini Nanayakkara
Quality control of the nervous system by autophagy - Noboru Mizushima

6:30PM - 11:00PM

Wednesday, 19th November

Lorne Common (Footy Oval)

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Wednesday, 19th November 11th International Symposium on Autophagy 2025

Session 5 - Cell Biology and Physiology II (Neurons, Metabolism)

Break

Session 5 - Cell Biology and Physiology II (Neurons, Metabolism) - Continue

Flash Talk II

The 11th ISA Group Photo

Lunch

Poster Session II

Session 6 - Mechanisms III (Selective autophagy, lysosome biology)

Break

Session 6 - Mechanisms III (Selective autophagy, lysosome biology) - Continue

Banquet